Mechanism of Action

Blitz 01 also known as polyionene, is a cationic amphiphilic biopolymer that enables killing the microbes through a unique functional mechanism. The image below shows how this biopolymer works to eliminate the microbes :

This polymer will first attach onto the cell membrane of the microbe through strong multivalent ionic interactions between the cationic charges in the polymer and anionic phosphate groups on the microbial membrane. Thereafter, the hydrophobic components in the polymer insert into the lipid domain of the microbial membrane. This leads to membrane disruption and membrane lysis, eventually microbial cell death. Because of the nature of multivalent interaction and physical membrane disruption, repeated use of this would mitigate development of antimicrobial resistance.

Unique properties of Blitz 01

Efficacy

  • Broad spectrum of efficacy

    Work effectively against bacteria, fungi and viruses

  • Fast acting

    Eliminate given microbes within 30 seconds

  • Mitigate antimicrobial resistance

    Unique membrane-lytic mechanism to kill off microbes and thus preventing development of resistance over time

  • Long lasting

    Offer continuous protection for up to 48 hours upon application

Safety

  • Safe on mammalian cells

    Multivalent positive charge that makes it highly selectivity towards microbes over mammalian cells

  • Safe on skin and body

    Macromolecular structure which does not penetrate skin to cause systemic side effect and skin irritation

  • Safe on environment

    Amide-Bonded that is stable under storage condition yet biodegradable by specific enzymes in environment